Catalytic Arylations with Challenging Substrates: From Air-Stable HASPO Preligands to Indole Syntheses and C-H-Bond Functionalizations

The development of novel ligands and their applications to transition-metal catalysis performed in our laboratory are ­summarized. These studies include the use of air-stable, modular heteroatom-substituted secondary phosphine oxides (HASPO) in cross-coupling reactions of challenging substrates, such as aryl and vinyl chlorides, fluorides, and tosylates.