gene2drug: a computational tool for pathway-based rational drug repositioning

Napolitano et al. (Sun,) studied this question.

www.synapsesocial.com/papers/69d9b8dba1d151c65f6850dc — DOI: https://doi.org/10.1093/bioinformatics/btx800

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. A review of connectivity map and computational approaches in pharmacogenomics· 2017 · 158 citations
2. The analysis of the drug–targets based on the topological properties in the human protein–protein interaction network· 2009 · 109 citations
3. In Silico Modeling of Liver Metabolism in a Human Disease Reveals a Key Enzyme for Histidine and Histamine Homeostasis· 2016 · 34 citations
4. How many drug targets are there?· 2006 · 3,493 citations
5. A review of connectivity map and computational approaches in pharmacogenomics· 2017 · 273 citations