Comparative Study of Haemodynamic Changes During Induction of General Anaesthesia: Propofol Versus Etomidate

BACKGROUND of general anaesthesia is a critical part of anaesthesia practice. An ideal inducing agent for general anaesthesia should haemodynamic stability, minimal respiratory side effects and rapid clearance. Sudden bronchospasm, hypotension, , respiratory depression and cardiovascular collapse are life threatening complications following induction. It is to use a safe agent with fewer adverse effects for this purpose. We wanted to compare the haemodynamic responses inducing with intravenous propofol versus etomidate utilizing the standard methods for the drugs. ideal induction agent for general anaesthesia should have haemodynamic stability, minimal respiratory side effects and rapid. Presently there are a number of induction agents available. Thiopental is the conventional induction agent discovered 1934 by John S. Lundy, known for rapid action and rapid awakening, 1 has an additional property of decreasing ICP in cases. Studies have showed that it causes peripheral vasodilatation, decrease in blood pressure, increase in heart and has direct negative ionotropic effect on heart. responses measured were heart rate, blood pressure, diastolic blood pressure and MAP. In our study, we found that, who received etomidate, when compared to propofol group, were haemodynamically stable during and 10 minutes induction and intubation. provides better haemodynamic stability during induction than propofol, in patients undergoing surgeries, under anaesthesia with endotracheal intubation.