Provocative testing methods, including 6-minute walk testing and cardiopulmonary exercise testing, provide valuable insight into the diagnosis, prognosis, and response to therapy in pulmonary vascular disease.
This review provides practical guidance on selecting and interpreting various exercise testing modalities for patients with pulmonary vascular disease.
Background: Most pulmonary vascular disease (PVD) is poorly modifiable and incurable even with effective therapy. Therefore, adaptation to stress, the reserve of the cardiopulmonary system, is important for assessment of patient function and prognosis. Methods that assess the adaptation to stress, especially exercise, provide valuable insight into diagnosis, prognosis, and response to therapy. Implications for Clinicians: We provide a comprehensive review of the indications, methodology, and interpretation, as well as practical information of the forms of provocative testing in PVD. We include 6-minute walk testing, noninvasive cardiopulmonary exercise testing (CPET), invasive CPET, and additional forms, including volume loading. Conclusions: Through a clear understanding of the methodology in the assessment of PVD, the clinician can determine which of these “tools of the trade” are best suited to the individual patient and situation.
Rischard et al. (Mon,) conducted a review in Pulmonary vascular disease. Provocative testing (6-minute walk testing, CPET, volume loading) was evaluated. Provocative testing methods, including 6-minute walk testing and cardiopulmonary exercise testing, provide valuable insight into the diagnosis, prognosis, and response to therapy in pulmonary vascular disease.
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