Transvenous temporary cardiac pacing therapy had an overall mean complication rate of 36.7%, which significantly decreased over time but remained high at 22.9% in the most recent period (p<0.001).
Systematic Review (n=4,546)
What are the indications, access routes, and complication rates associated with transvenous temporary cardiac pacing therapy?
Transvenous temporary pacing is associated with a high complication rate (36.7% historically, 22.9% recently), and the majority of patients subsequently require permanent pacemaker therapy.
p-value: p=<0.001
Transvenous temporary cardiac pacing therapy (TV-TP) is widely used to treat life-threatening arrhythmias. Yet aggregated evidence on TV-TP is limited. We conducted a systematic scoping review to evaluate indications, access routes and complications of TV-TP, as well as permanent pacemaker therapy (PPM) following TV-TP. Clinical studies concerning TV-TP were identified in Ovid MEDLINE. Case studies and studies lacking complication rates were excluded. To assess complication incidence over time, differences in mean complication rates between 10-year intervals since the introduction of TV-TP were evaluated. We identified 1398 studies, of which 32 were included, effectively including 4546 patients. Indications varied considerably; however TV-TP was most commonly performed in atrioventricular block (62.7%). The preferred site of access was the femoral vein (47.2%). The mean complication rate was 36.7%, of which 10.2% were considered serious. The incidence of complications decreased significantly between 10-year interval groups, but remained high in the most recent time period (22.9%) (analysis of variance; p < 0.001). PPM was required in 64.2% of cases following TV-TP. Atrioventricular block was the primary indication for TV-TP; however indications varied widely. The femoral vein was the most frequent approach. Complications are common in patients undergoing TV-TP. Although a decrease has been observed since its introduction, the clinical burden remains significant. The majority of patients who underwent TV-TP required PPM therapy.
Tjong et al. (Wed,) conducted a systematic review in Life-threatening arrhythmias requiring transvenous temporary cardiac pacing (n=4,546). Transvenous temporary cardiac pacing therapy (TV-TP) was evaluated on Complication incidence over time (10-year intervals) (p=<0.001). Transvenous temporary cardiac pacing therapy had an overall mean complication rate of 36.7%, which significantly decreased over time but remained high at 22.9% in the most recent period (p<0.001).
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