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. 2D NMR spectra enabled with this method revealed that the tethered palmitic acid perturbs nearly every secondary structural region of AcpP. This technique will allow previously unachievable structural studies of unstable acyl-ACP species, contributing to the understanding of these complex biosynthetic pathways.
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Terra Sztain
University of Michigan
Thomas G. Bartholow
University of Wisconsin–Eau Claire
J. Andrew McCammon
University of California, San Diego
Biochemistry
University of California, San Diego
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Sztain et al. (Fri,) studied this question.
synapsesocial.com/papers/6a03cbb444bc058a01d7c107 — DOI: https://doi.org/10.1021/acs.biochem.9b00612
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