The study provides a freely available database and computational tools for simulating and analyzing arterial pulse waves across different ages to evaluate hemodynamics in silico.
First, a comprehensive literature review of changes in cardiovascular properties with age was performed. Second, an approach for simulating pulse waves (PWs) at different ages was designed and verified against in vivo data. Third, a PW database was created, and its utility was illustrated through three case studies investigating the determinants of PW indexes. Fourth, the database and tools for creating the database, analyzing PWs, and replicating the case studies are freely available.
Charlton et al. (Fri,) studied this question.