Newly detected atrial fibrillation after acute stroke lacks a standardized definition, and its pathophysiology remains incompletely understood, possibly involving autonomic and humoral alterations.
This narrative review summarizes the definition, epidemiology, and pathophysiology of newly detected atrial fibrillation following acute stroke.
Cardiac arrhythmias occur frequently in patients with acute stroke, with atrial fibrillation (AF) being the most common. Newly detected AF may lead to increased risk of ischemic stroke, which in turn generates stroke recurrence and adverse outcomes. Currently, most studies are focusing on the role of AF in ischemic stroke and attributing cryptogenic ischemic stroke to previously undetected AF. However, in these studies, subjects used to have neither symptoms of palpitation nor evidence of AF. A better understanding of this association will contribute to the management and therapy for patients after clinical decisions regarding stroke patients. Currently, the definition of newly detected AF has not come to an agreement, and the pathophysiology remains incompletely understood, possibly involving complex alterations in both the autonomic network and humoral regulation. Therefore, this review aims to introduce the definition and epidemiology of newly detected AF after stroke with updated information and elucidate the potential pathophysi-ology, such as autonomic imbalance, catecholamine surge, poststroke systematic inflammation, and microvesicles and microRNAs.
Wang et al. (Tue,) conducted a review in Newly detected atrial fibrillation after acute stroke. Newly detected atrial fibrillation was evaluated. Newly detected atrial fibrillation after acute stroke lacks a standardized definition, and its pathophysiology remains incompletely understood, possibly involving autonomic and humoral alterations.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: