October 21, 2019Open Access
Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study
Key Points
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Abstract
Age-treatment subgroup analyses in Cochrane intervention reviews were frequently planned but rarely conducted, and implications of detected interactions were not discussed in the reviews or mentioned in common clinical resources. When subgroup analyses are performed, authors should report the findings, compare the results to previous studies, and outline any potential impact on clinical care.