In Japanese patients receiving cardiac resynchronization therapy, the response rate did not differ significantly among those with narrow (<130 ms), mid (130-150 ms), and wide (≥150 ms) QRS durations (83.6%, 91.3%, and 92.4%, respectively).
Observational (n=537)
No
Does a narrow QRS duration (<130 ms) still allow for response to cardiac resynchronization therapy in lightweight Japanese patients?
In Japanese patients, QRS duration depends on body size, and CRT response rates remain high even in patients with a narrow QRS (<130 ms), suggesting a strict >130 ms cutoff may not be necessary for smaller patients.
Absolute Event Rate: 83.6% vs 92.4%
Abstract A prolonged QRS duration (QRSd) is promising for a response to cardiac resynchronization therapy (CRT). The variation in human body sizes may affect the QRSd. We hypothesized that conduction disturbances may exist in Japanese even with a narrow ( 130 ms may not be necessary, and the current JCS guidelines appear to be appropriate.
Nakai et al. (Wed,) conducted a observational in Heart failure (CRT candidates) (n=537). Narrow QRS duration (<130 ms) vs. Mid (130-150 ms) and wide (≥150 ms) QRS duration was evaluated on CRT response rate (functional and echocardiographic improvement at 6 months). In Japanese patients receiving cardiac resynchronization therapy, the response rate did not differ significantly among those with narrow (<130 ms), mid (130-150 ms), and wide (≥150 ms) QRS durations (83.6%, 91.3%, and 92.4%, respectively).