A novel 7-item clinical score successfully predicted the probability of echocardiographic left ventricular hypertrophy in hypertensive patients without ECG LVH (P<0.001).
Observational (n=2,150)
p-value: p=<0.001
Background It is debated whether echocardiography should be part of the diagnostic workup in all hypertensive patients. We identified some factors potentially associated with left ventricular hypertrophy ( LVH ) at echocardiography in untreated hypertensive patients. Methods and Results We studied 2150 patients without LVH at ECG . All patients underwent standard 12‐lead ECG and echocardiography. Mean age was 48.7 years, and mean office blood pressure was 154/97 mm Hg. Prevalence of echocardiographic LVH ( LV mass >47.0 g/m 2.7 in women and >50.0 g/m 2.7 in men) was 37.1%. We developed a nomogram based on 7 items (age, smoking, body mass index, office systolic and diastolic blood pressure, Cornell voltage, and chronic kidney disease) on the basis of a multivariable logistic regression analysis. We internally validated the model by bootstrap recalibration and obtained a calibration curve to assess agreement in the validation data set. Probability of LVH at echocardiography ranged from 90% (score, ≥180 points). Proportion of patients with LVH progressively increased with the total score (χ 2 =444.8; P 136 in men and >124 in women.
Mancusi et al. (Mon,) conducted a observational in Hypertension (n=2,150). 7-item clinical score was evaluated on Left ventricular hypertrophy (LVH) at echocardiography (p=<0.001). A novel 7-item clinical score successfully predicted the probability of echocardiographic left ventricular hypertrophy in hypertensive patients without ECG LVH (P<0.001).