Patients with transthyretin cardiac amyloidosis
Mortalityhard clinical
Echocardiographic assessment of systolic and diastolic function, along with the presence of severe aortic stenosis, provides important prognostic information regarding survival in transthyretin cardiac amyloidosis.
The three distinct genotypes present with varying degrees of severity. Echocardiography indicates a complex pathophysiology in which both systolic and diastolic function are independently associated with mortality. The presence of severe AS was independently associated with significantly reduced patient survival.
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Liza Chacko
Raffaele Martone
Francesco Bandera
European Heart Journal
University College London
University of Milan
University of Florence
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Chacko et al. (Sat,) studied this question.
www.synapsesocial.com/papers/69aea782e8b2090a71ff9e76 — DOI: https://doi.org/10.1093/eurheartj/ehz905