Hypertrophic cardiomyopathy patients with preserved right ventricular ejection fraction had significantly impaired global right ventricular longitudinal peak strain compared to healthy controls (-6.45% vs -9.54%, p=0.007).
Observational (n=114)
No
Does CMR-TT detect subclinical right ventricular myocardial deformation in hypertrophic cardiomyopathy patients with preserved right ventricular ejection fraction compared to healthy controls?
CMR-TT can detect subclinical right ventricular myocardial deformation in HCM patients with preserved RVEF, revealing that impairment is more severe in the presence of right ventricular hypertrophy and late gadolinium enhancement.
Absolute Event Rate: -6.45% vs -9.54%
p-value: p=0.007
To assess the global and regional right ventricular (RV) deformation in hypertrophic cardiomyopathy (HCM) patients with preserved right ventricular ejection fraction (RVEF) using 3.0-T cardiovascular magnetic resonance tissue tracking (CMR-TT). Eighty-two HCM patients and 32 age- and sex-matched healthy controls were enrolled. HCM patients were divided into groups depending on the presence or absence of right ventricular hypertrophy (RVH), RV late gadolinium enhancement (RV-LGE), and left ventricular outflow tract obstruction (LVOTO), respectively. The RV global and apical longitudinal peak strain (LPS) in HCM patients with RVH were significantly lower than that in HCM patients without RVH and controls (P 0.05). CMR-TT was able to detect subclinical RV myocardial deformation prior to RVEF impairment, which was more severe in the presence of RVH and RV-LGE.
Li et al. (Thu,) conducted a observational in Hypertrophic cardiomyopathy with preserved right ventricular ejection fraction (n=114). Hypertrophic cardiomyopathy vs. Healthy controls was evaluated on Global right ventricular longitudinal peak strain (LPS) (p=0.007). Hypertrophic cardiomyopathy patients with preserved right ventricular ejection fraction had significantly impaired global right ventricular longitudinal peak strain compared to healthy controls (-6.45% vs -9.54%, p=0.007).