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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComputer-assisted synthetic analysis. Methods for machine generation of synthetic intermediates involving multistep look-aheadE. J. Corey, W. Jeffrey Howe, and David A. PensakCite this: J. Am. Chem. Soc. 1974, 96, 25, 7724–7737Publication Date (Print):December 1, 1974Publication History Published online1 May 2002Published inissue 1 December 1974https://pubs.acs.org/doi/10.1021/ja00832a019https://doi.org/10.1021/ja00832a019research-articleACS PublicationsRequest reuse permissionsArticle Views301Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Corey et al. (1974) studied this question.