Major vascular complication after transfemoral transcatheter aortic valve replacement was associated with a significantly increased risk of 3-year mortality (HR 2.01) compared to no complication.
Observational (n=1,842)
Yes
Does major vascular complication (MVC) access site status and bleeding severity impact 3-year mortality in patients undergoing TF-TAVR?
Major vascular complications after TF-TAVR significantly increase 3-year mortality, with non-access site-related complications and severe access site-related complications requiring massive transfusion driving the worst outcomes.
Effect estimate: HR 2.01 (95% CI 1.16-3.62)
Absolute Event Rate: 40.8% vs 24.3%
p-value: p=<0.001
Background:The aim of this study was to investigate the impact of anatomical site status and major vascular complication (MVC) severity on the outcome of transfemoral transcatheter aortic valve replacement (TF-TAVR).
Laakso et al. (Thu,) conducted a observational in Severe aortic stenosis undergoing transfemoral transcatheter aortic valve replacement (n=1,842). Major vascular complication (MVC) vs. No major vascular complication was evaluated on 3-year all-cause mortality (HR 2.01, 95% CI 1.16-3.62, p=<0.001). Major vascular complication after transfemoral transcatheter aortic valve replacement was associated with a significantly increased risk of 3-year mortality (HR 2.01) compared to no complication.
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