Does acute preprocedural administration of colchicine reduce inflammation and myocardial injury in patients undergoing PCI?
Acute preprocedural colchicine reduces post-PCI inflammatory markers but fails to prevent PCI-related myocardial injury.
Acute preprocedural administration of colchicine attenuated the increase in interleukin-6 and high-sensitivity C-reactive protein concentrations after PCI when compared with placebo but did not lower the risk of PCI-related myocardial injury. Registration: URL: https://www.clinicaltrials.gov; Unique Identifiers: NCT02594111, NCT01709981.
Shah et al. (Wed,) studied this question.