The oxygen desaturation index showed significant heterogeneity in accuracy compared to the apnea-hypopnea index, with sensitivities ranging from 32% to 98.5% and specificities from 47.7% to 98%.
Systematic Review
Does the oxygen desaturation index (ODI) accurately diagnose obstructive sleep apnea compared to the apnea-hypopnea index (AHI) in adults?
Screening with oximetry using a 4% ODI ≥ 15 events/hour may be useful for diagnosing adult OSA, though significant heterogeneity exists in current studies.
OBJECTIVES: Intermittent hypoxemia is a risk factor for developing complications in obstructive sleep apnea (OSA) patients. The objective of this systematic review was to identify articles evaluating the accuracy of the oxygen desaturation index (ODI) as compared with the apnea-hypopnea index (AHI) and then provide possible values to use as a cutoff for diagnosing adult OSA. STUDY DESIGN: Systematic Review of Literature. METHODS: PubMed, the Cochrane Library, and SCOPUS databases were searched through November 2019. RESULTS: , and AHI range: 0.5-62 events/hour). Five studies compared ODI and AHI simultaneously, and three had a week to months between assessments. Sensitivities ranged from 32% to 98.5%, whereas specificities ranged from 47.7% to 98%. Significant heterogeneity was present; however, for studies reporting data for a 4% ODI ≥ 15 events/hour, the specificity for diagnosing OSA ranged from 75% to 98%, and only one study reported the positive predictive value, which was 97%. Direct ODI and AHI comparisons were not made because of different hypopnea scoring, different oxygen desaturation categories, and different criteria for grading OSA severity. CONCLUSION: Significant heterogeneity exists in studies comparing ODI and AHI. Based on currently published studies, consideration should be given for diagnosing adult OSA with a 4% ODI of ≥ 15 events/hour and for recommending further evaluation for diagnosing OSA with a 4% ODI ≥ 10 events/hour. Screening with oximetry may be indicated for the detection of OSA in select patients. Further study is needed before a definitive recommendation can be made. Laryngoscope, 131:440-447, 2021.
Rashid et al. (Sat,) conducted a systematic review in Obstructive sleep apnea (OSA). Oxygen desaturation index (ODI) vs. Apnea-hypopnea index (AHI) was evaluated on Accuracy (sensitivity and specificity) of ODI for diagnosing OSA. The oxygen desaturation index showed significant heterogeneity in accuracy compared to the apnea-hypopnea index, with sensitivities ranging from 32% to 98.5% and specificities from 47.7% to 98%.