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cRGD-ZW800-1 enabled fluorescence imaging of colon cancer in both open and minimal invasive surgeries. Further development of cRGD-ZW800-1 for widespread use in cancer surgery may be warranted given the ubiquitous overexpression of various integrins on different types of tumors and their vasculature.
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Kim S. de Valk
Leiden University
Marion M. Deken
Leiden University Medical Center
Henricus J.M. Handgraaf
Jeroen Bosch Ziekenhuis
Clinical Cancer Research
Leiden University Medical Center
Centre for Human Drug Research
Combat Capabilities Development Command Soldier Center
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Valk et al. (Tue,) studied this question.
synapsesocial.com/papers/69d791643fae90fd6048fcfa — DOI: https://doi.org/10.1158/1078-0432.ccr-19-4156