Increased NT-proBNP levels significantly correlated with impaired renal function in patients with heart failure, though this relationship decreased in patients over 85 years of age.
Observational (n=374)
No
NT-proBNP levels in elderly patients with heart failure should be evaluated considering both the patient's age group and renal impairment.
Effect estimate: r=-0.25
p-value: p=<0.05
Objectives: The aim of this study was to investigate the hypothesis that increased NT pro-BNP levels may be associated with impaired cardiac and renal function in elderly and middle-aged patients. Therefore, we have examined possible relationships between NT-PROBNP levels and other tests in every aspect. Methods: The data of NT-proBNP, Urea, Creatinine, GFR, CK-MB, Trop I and CRP tests of 374 patients admitted to our hospital between September 2019 and November 2019 were evaluated retrospectively. In order to determine the effect of renal dysfunction on NT-proBNP test levels, four study groups, one control group, were formed according to age and NT-proBNP test levels. Results: NT-proBNP levels below 81-102 years with NT-proBNP levels> 10000 pg / ml. (respectively, r: 0.25, P <0.05; r: 0.32, P <0.01; r: -0.25, P <: 0.05; r: 0.33, P <0 , 01). Conclusion: This study showed that NT pro-BNP levels in elderly patients with heart failure and renal dysfunction should be evaluated by considering the patient's renal impairment as well as the age group.
Ünsal Gündoğdu (Wed,) conducted a observational in Heart failure and renal dysfunction (n=374). NT-proBNP testing vs. Normal NT-proBNP levels (<125 pg/ml) was evaluated on Correlation between NT-proBNP and GFR in patients aged 81-102 years with NT-proBNP >10000 pg/ml (r=-0.25, p=<0.05). Increased NT-proBNP levels significantly correlated with impaired renal function in patients with heart failure, though this relationship decreased in patients over 85 years of age.
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