July 22, 2020

Peripheral inflammation exacerbates α‐synuclein toxicity and neuropathology in Parkinson's models

Key Points

Key points are not available for this paper at this time.

Abstract

The fine management of both peripheral and central inflammation may offer a promising therapeutic approach to prevent or slow down some behavioural aspects in α-synucleinopathies.

Ask AI

Helpful

Bookmark

Ask AI

Helpful

Bookmark

Cite This Study

Vitola et al. (Wed,) studied this question.

synapsesocial.com/papers/69d75d71f182769aa8b8ab27 https://doi.org/https://doi.org/10.1111/nan.12644

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1β in the substantia nigra2006 · 228 citations
2Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients1994 · 991 citations
3Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury2017 · 113 citations
4A Pathologic Cascade Leading to Synaptic Dysfunction in -Synuclein-Induced Neurodegeneration2010 · 361 citations
5Barriers and Advances in Kidney Preservation2018 · 368 citations