Mortality Rates in Acute Myocardial Infarction. Ii. A Proposed Method for Measuring Quantitatively Severity of Illness on Admission to the Hospital

Article1 November 1953MORTALITY RATES IN ACUTE MYOCARDIAL INFARCTION. II. A PROPOSED METHOD FOR MEASURING QUANTITATIVELY SEVERITY OF ILLNESS ON ADMISSION TO THE HOSPITALSIDNEY SCHNUR, M.D., F.A.C.P.SIDNEY SCHNUR, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-5-1018 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn any clinical investigation whose purpose is to gauge the effect of therapy upon the mortality rate, it is axiomatic that treated and control groups must first be equivalent in all factors affecting prognosis if the study is to yield sound and valid conclusions. This would be especially true in a disease such as acute myocardial infarction, in which the mortality rate has been reported to range from 8 per cent1to 78 per cent.2Unfortunately, the large number of prognostic factors in this disease has made it difficult to determine whether two groups are in fact equal. The solution...Bibliography1. MasterJaffeDack AMHLS: The treatment and immediate prognosis of coronary artery thrombosis, Am. Heart J. 12: 549, 1936. CrossrefGoogle Scholar2. Newman M: Coronary occlusion in young adults, Lancet 2: 409, 1946. CrossrefMedlineGoogle Scholar3. NicholPage ESSW: Dicumarol therapy in acute coronary thrombosis; results in fifty attacks, J. Florida M. A. 32: 365, 1946. MedlineGoogle Scholar4. MullinsHolzPurvisBaileyKeister WLMKJDWRSR: The treatment of acute coronary occlusion with anticoagulants, Pennsylvania M. J. 53: 245, 1950. Google Scholar5. GreismanMarcus HAM: Acute myocardial infarction: detailed study of Dicumarol therapy in seventy-five consecutive cases, Am. Heart J. 36: 600, 1948. CrossrefMedlineGoogle Scholar6. WrightMarpleBeck ISCDDF: Report of the Committee For the Evaluation of Anticoagulants in the Treatment of Coronary Thrombosis with Myocardial Infarction, Am. Heart J. 36: 801, 1948. CrossrefMedlineGoogle Scholar7. Hill B: Principles of medical statistics, 1950, New York, Oxford University Press, p. 194. Google Scholar8. ZeluffField GWWW: Anticoagulants in treatment of coronary occlusion with myocardial infarction. A study of eighty cases, New York State J. Med. 50: 1737, 1950. MedlineGoogle Scholar9. Schnur S: Mortality and other studies questioning the evidence for and value of routine anticoagulant therapy in acute myocardial infarction, Circulation 7: 855, 1953. CrossrefMedlineGoogle Scholar10. Rytand DA: Anticoagulants in coronary thrombosis with myocardial infarction, Arch. Int. Med. 88: 207, 1951. CrossrefGoogle Scholar11. TullochGilchrist JAAR: Anticoagulants in treatment of coronary thrombosis, Brit. M. J. 2: 965, 1950. CrossrefMedlineGoogle Scholar12. RussekZohmanDoernerRussekWhite HIBLAAASLG: Age and survival in cases of acute myocardial infarction, J. A. M. A. 147: 1731, 1951. CrossrefMedlineGoogle Scholar13. Schnur S: Mortality rates in acute myocardial infarction. III. The relation of patient's age to prognosis. To be published. Google Scholar14. Schnur S: Mortality rates in acute myocardial infarction. IV. Prognostic significance of shock and congestive heart failure with a general discussion of factors contributing to the mortality rate. To be published. Google Scholar15. RosenbaumLevine FSSA: Clinical and electrocardiographic features of acute myocardial infarction on immediate prognosis, Arch. Int. Med. 68: 913, 1941. CrossrefGoogle Scholar16. RosenbaumLevine FSSA: Prognostic value of various clinical and electrocardiographic features of acute myocardial infarction: ultimate prognosis, Arch. Int. Med. 68: 1215, 1941. CrossrefGoogle Scholar17. WoodBarnes RMAR: Factors influencing immediate mortality rate following acute coronary occlusion, Proc. Staff Meet., Mayo Clin. 16: 341, 1941. Google Scholar18. DoscherPoindexter NPH: Myocardial infarction without anticoagulant therapy, Am. J. Med. 8: 623, 1950. CrossrefMedlineGoogle Scholar19. RussekZohmanWhiteDoerner HIBLLGAA: Indications for bishydroxycoumarin (Dicumarol) in acute myocardial infarction, Circulation 5: 707, 1952. CrossrefMedlineGoogle Scholar20. SchnurGlassGoensRosenblattSpikes SWGRWHDGA: Further studies of mortality rates in acute myocardial infarction questioning the value of routine anticoagulant therapy. To be published. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 20, 1953.From the Department of Medicine, Baylor University College of Medicine, and the Jefferson Davis Hospital, Houston, Texas. 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THE "NORMAL" YEARLY VARIATION, AND THE EFFECT OF HOSPITAL ADMISSION POLICY*SIDNEY SCHNUR, M.D., F.A.C.P. 1 November 1953Volume 39, Issue 5Page: 1018-1025KeywordsAcute myocardial infarctionDeath ratesHospital medicineMortality ePublished: 1 December 2008 Issue Published: 1 November 1953 PDF downloadLoading ...