Does spironolactone reduce blood pressure in patients with resistant hypertension?
Spironolactone provides substantial blood pressure reduction at 3 months in patients with resistant hypertension.
This meta-analysis fully evaluated the antihypertensive effect of spironolactone compared with placebo, alternative drugs, renal nerve denervation and no treatment. Spironolactone can result in a substantial BP reduction in patients with RH at 3 months.
Chen et al. (Wed,) studied this question.
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