Are higher and lower serum potassium levels independent predictors of cardiovascular death in the PARADIGM-HF Trial?
In the PARADIGM-HF trial, both hyperkalemia and hypokalemia independently predicted cardiovascular death, likely acting as risk markers rather than direct mediators.
Although both higher and lower potassium levels were independent predictors of cardiovascular death, potassium abnormalities may mainly be markers rather than mediators of risk for death.
Ferreira et al. (Fri,) studied this question.
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