September 30, 2020Open Access

Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis

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Abstract

to mammals. Finally, we demonstrate that both trBax and trBak BH3 peptides bind selectively to human Bcl-2 homologs to sensitize cancer cells to chemotherapy treatment.

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Authors

Nikolay Popgeorgiev

Université Claude Bernard Lyon 1

D Jaison

The University of Melbourne

Lea Jabbour

Centre National de la Recherche Scientifique

Journals

Science Advances

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Centre National de la Recherche Scientifique

Inserm

The University of Melbourne

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Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis

Key Points

Abstract

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Discussion

Authors

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References and Citations

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