Patients with suspect coronary microvascular dysfunction exhibited significantly higher state sadness during maximal exertion (15.9%) compared to other groups, with no differences in other psychological factors.
Cross-Sectional (n=295)
No
Are psychological factors and acute emotions different in patients with suspect coronary microvascular dysfunction compared to other patients undergoing SPECT imaging?
Patients with suspect coronary microvascular dysfunction undergoing SPECT imaging exhibit higher levels of state sadness, but no other significant differences in psychological factors compared to other patient groups.
Absolute Event Rate: 15.9% vs 9.7%
p-value: p=0.029
Patients with myocardial ischemia in the absence of obstructive coronary artery disease (CAD) often experience anginal complaints and are at risk of cardiac events. Stress-related psychological factors and acute negative emotions might play a role in these patients with suspect coronary microvascular dysfunction (CMD). 295 Patients (66.9 ± 8.7 years, 46% women) undergoing myocardial perfusion single-photon-emission computed tomography (MPI-SPECT), were divided as follows: (1) a non-ischemic reference group (n = 136); (2) patients without inducible ischemia, but with a history of CAD (n = 62); (3) ischemia and documented CAD (n = 52); and (4) ischemia and suspect CMD (n = 45). These four groups were compared with regard to psychological factors and acute emotions. Results revealed no differences between the groups in psychological factors (all P > .646, all effect sizes d .448). Suspect CMD was not associated with more negative psychological factors compared to other groups. State sadness was significantly higher for patients with suspect CMD, whereas no differences in state anxiety and other psychological factors were found.
Bekendam et al. (Tue,) conducted a cross-sectional in Suspect coronary microvascular dysfunction (n=295). Suspect coronary microvascular dysfunction vs. Non-ischemic reference, history of CAD, and ischemic CAD was evaluated on State sadness during maximal exertion (p=0.029). Patients with suspect coronary microvascular dysfunction exhibited significantly higher state sadness during maximal exertion (15.9%) compared to other groups, with no differences in other psychological factors.
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