Does Dixon cardiac MR Fingerprinting provide comparable quantitative mapping and image quality compared to conventional sequences in patients with suspected cardiovascular disease?
Dixon cardiac MR fingerprinting is a clinically feasible technique that can simultaneously quantify T1, T2, and fat fraction in a single breath-hold with image quality comparable to conventional methods.
BACKGROUND: , and fat fraction (FF) maps. PURPOSE: To assess Dixon cardiac MRF repeatability in healthy subjects and its clinical feasibility in a cohort of patients with cardiovascular disease. POPULATION: T1MES phantom, water-fat phantom, 11 healthy subjects and 19 patients with suspected cardiovascular disease. STUDY TYPE: Prospective. FIELD STRENGTH/SEQUENCE: -GRASE), 6-echo gradient rewound echo (GRE), and Dixon cardiac MRF. ASSESSMENT: and synthetic extracellular volume (ECV) maps were assessed in 19 patients in comparison to conventional sequences. Measurements in patients were performed in the septum and in late gadolinium enhanced (LGE) areas and assessed using mean value distributions, correlation, and Bland-Altman plots. Image quality and diagnostic confidence were assessed by three experts using 5-point scoring scales. STATISTICAL TESTS: Paired Wilcoxon rank signed test and paired t-tests were applied. Statistical significance was indicated by *(P < 0.05). RESULTS: (P = 0.17) and synthetic ECV (P = 0.19) measurements were observed in patients. DATA CONCLUSION: , and fat fraction maps in a single breath-hold scan with similar or better image quality than conventional methods in patients. LEVEL OF EVIDENCE: 2. TECHNICAL EFFICACY STAGE: 2.
Jaubert et al. (Thu,) studied this question.