March 15, 2021Open Access

Candida tropicalis distribution and drug resistance is correlated with ERG11 and UPC2 expression

DWDan WangKing University NANa AnImation (United States)YYYuwei YangUniversity of Electronic Science and Technology of China

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Abstract

Overexpression of the ERG11 and UPC2 genes in C. tropicalis could increase resistance to azole antifungal drugs. The routine testing for ERG11 and UPC2 in high-risk patients in key departments would provide a theoretical basis for the rational application of azole antifungal drugs.

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