What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Acute myocardial infarction (n=240). Intervention: Female gender vs. Male gender. Primary outcome: Presence of atypical clinical presentations (p=0.005).

January 1, 2021Open Access

Gender divides in the clinical profiles of patients with acute myocardial infarction at a tertiary care center in South India

LRL. RamamoorthyJawaharlal Institute of Post Graduate Medical Education and Research NGNeethuM GeorgeJawaharlal Institute of Post Graduate Medical Education and Research SSSanthosh SatheeshGuntur Medical College

Key Result

Women with acute myocardial infarction presented with significantly more atypical symptoms (85.0%) compared to men (70.0%).

Study Design

Type

Cross-Sectional (n=240)

Multicenter

Structured PICO

Do risk factors, clinical manifestations, and coronary angiography findings differ between men and women presenting with acute myocardial infarction?

Population

240 consecutive patients (120 male, 120 female) admitted with acute myocardial infarction, who had survived and been stabilized, at a tertiary care center in South India.

Outcome

Gender-based differences in risk factors, clinical manifestations, and coronary angiography findings

Women with acute myocardial infarction present more frequently with atypical symptoms and non-obstructive coronary disease compared to men, highlighting the need for gender-specific awareness to prevent delayed care.

Main Result

Absolute Event Rate: 85% vs 70%

p-value: p=0.005

Limitations

Recall bias due to self-structured questionnaire and interview method
Limited sample size

Abstract

BACKGROUND: Early identification of myocardial infarction (MI) is a determinant in the provision of appropriate treatment modalities. The focus of the present study is on the identification of gender-based differences in risk factors, clinical manifestations, and coronary angiography findings in patients presenting with MI. MATERIALS AND METHODS: A cross-sectional study was conducted among patients admitted with MI at a tertiary care center in South India during March 2016 to June 2017. Selected 120 male and 120 female consecutive patients admitted with acute MI, who had survived and been stabilized. Data was collected using a pre-tested structure data sheet. Appropriate parametric and nonparametric tests were used to analyze the data. RESULTS: = 0.008, respectively). CONCLUSION: Public education is needed on the atypical presentations which are common with women than in men. The public should, therefore, be informed of those symptoms and how to recognize them so that they may seek medical care promptly.

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