Combined physical and mental stress significantly increased free fatty acids, norepinephrine, diastolic blood pressure, peripheral vascular resistance, and arterial distensibility (p < .05).
Does combined physical and mental stress alter fatty acids, norepinephrine, and hemodynamics in healthy individuals?
Acute physical and mental stress increases free fatty acids, norepinephrine, and peripheral vascular resistance, suggesting a potential pathophysiological mechanism for hypertension.
p-value: p=< .05
Hypertension is often associated with metabolic changes. The sustained increase in sympathetic activity is related to increased blood pressure and metabolic changes. Environmental stimuli may be related to increased sympathetic activity, blood pressure, and metabolic changes, especially in genetically predisposed individuals. The aim of this study was to evaluate the response of fatty acids to physical and mental stress in healthy volunteers and the hemodynamic, hormonal, and metabolic implications of these stimuli. Fifteen healthy individuals with a mean age of 31 ± 7 years, of both sexes, were evaluated. They were assessed at baseline and after combined physical and mental stress (isometric exercise test, Stroop color test). Blood samples were collected at baseline and after stimulation for glucose, insulin, fatty acid, and catecholamine levels. Blood pressure, heart rate, cardiac output, systemic vascular resistance, and distensibility of the large and small arteries were analyzed. The data obtained at baseline and after stimuli were from the same individual, being the control itself. Compared to baseline, after physical and mental stress there was a statistically significant increase (p < .05) in free fatty acids, norepinephrine, diastolic blood pressure, peripheral vascular resistance, and distensibility of the large and small arteries. In conclusion, the combination of physical and mental stress raised fatty acids, norepinephrine, diastolic blood pressure, and peripheral vascular resistance in healthy individuals.
Motta et al. (Fri,) conducted a other in Healthy individuals (n=15). Combined physical and mental stress (isometric exercise test, Stroop color test) vs. Baseline (self-controlled) was evaluated on Changes in free fatty acids, norepinephrine, diastolic blood pressure, peripheral vascular resistance, and arterial distensibility (p=< .05). Combined physical and mental stress significantly increased free fatty acids, norepinephrine, diastolic blood pressure, peripheral vascular resistance, and arterial distensibility (p < .05).