Obesity significantly hindered the achievement of target blood pressure in outpatients with arterial hypertension (OR 4.78), with only 31.3% of all hypertensive patients reaching their target.
Cross-Sectional (n=111)
Open-label
No
Target blood pressure is achieved in only about a third of outpatients with hypertension, with male sex, obesity, and concomitant pathologies being significant barriers to adequate control.
Effect estimate: OR 4.78 (95% CI 1.14-20.29)
p-value: p=0.033
AIM: Assessment of the frequency of reaching the target level of blood pressure (BP) and the factors affecting it in outpatients with arterial hypertension (AH). MATERIALS AND METHODS: An open, one-stage, comparative study involving 64 patients with hypertension and 47 without hypertension at the age of 40 to 59 years. All patients underwent physical examination, assessment of cardiovascular risk (CVR), 24-hour blood pressure monitoring (ABPM), echocardiography (ECHOCG), color duplex scanning of brachiocephalic arteries. RESULTS: Patients with hypertension and comparison groups were comparable in age, sex, smoking, history of myocardial infarction. 1st degree of hypertension was present in 26.6%, 2nd in 40.6%, 3rd in 12.5% of patients. Obesity was detected in 24.3% of patients and all patients with obesity had AH. The SCORE score in individuals with hypertension was 4.94.5; in the comparison group, 2.32.6 (p0.001). Non-stenosing atherosclerosis was present in 54.8% and 88%, p=0.020, and atherosclerotic plaque in the vascular lumen was present in 45.3% and 12% of patients with and without hypertension, respectively (p0.001). 68.8% were constantly treated, and the target BP was reached in 31.3% of patients with hypertension. Male gender (OR 1.68; 95% CI 1.6828.49; p=0.007), obesity (OR 4.78; 95% CI 1.1420.29; p=0.033), concomitant pathology (OR 3.09; 95% CI 1.029.37; p=0.046) were negative, and dyslipidemia (OR 0.10; 95% CI 0.010.84; p=0.033) was positive, affecting the achievement of the target level of blood pressure. CONCLUSION: The target level of blood pressure was achieved in 31.3% of outpatients with hypertension, mainly in women. Among patients who did not reach the target level of blood pressure, men, individuals with high SSR and obesity predominated. Concomitant pathology and obesity are negative, and dyslipidemia was positively associated with the achievement of the target level of blood pressure, which must be taken into account when developing measures for prevention and treatment.
Ларина et al. (Sun,) conducted a cross-sectional in Arterial hypertension (n=111). Standard outpatient antihypertensive therapy was evaluated on Association of obesity with failure to achieve target blood pressure (OR 4.78, 95% CI 1.14-20.29, p=0.033). Obesity significantly hindered the achievement of target blood pressure in outpatients with arterial hypertension (OR 4.78), with only 31.3% of all hypertensive patients reaching their target.