A higher cardiovascular health score was associated with lower baseline and follow-up brachial-ankle pulse wave velocity, which increased overall from a median of 1340 cm/s to 1400 cm/s over 4 years.
Cohort (n=1,315)
Does a better baseline cardiovascular health profile reduce the progression of arterial stiffness in cardiovascular disease-free adults?
A better baseline cardiovascular health profile is associated with slower progression of arterial stiffness over 4 years in disease-free adults.
OBJECTIVE: Arterial stiffness may be an intermediary biological pathway involved in the association between cardiovascular health (CVH) and cardiovascular disease. We aimed to evaluate the effect of CVH on progression of brachial-ankle pulse wave velocity (baPWV) over approximately 4 years. METHODS: We included 1315 cardiovascular disease-free adults (49±12 years) who had two checkups from 2010 to 2019. CVH metrics (current smoking, body mass index, total cholesterol, blood pressure, and fasting plasma glucose) were assessed at baseline, and the number of ideal CVH metrics and CVH score were calculated. Additionally, baPWV was examined at baseline and follow-up. RESULTS: Median baPWV increased from 1340 cm/s to 1400 cm/s, with an average annual change in baPWV of 15 cm/s. More ideal CVH metrics and a higher CVH score were associated with lower baseline and follow-up baPWV, and the annual change in baPWV, even after adjustment for confounding variables. Associations between CVH parameters and baseline and follow-up baPWV remained robust in different sex and age subgroups, but they were only able to predict the annual change in baPWV in men and individuals older than 50 years. CONCLUSIONS: Our findings highlight the benefit of a better baseline CVH profile for progression of arterial stiffness.
Sang et al. (Mon,) conducted a cohort in Cardiovascular disease-free (n=1,315). Cardiovascular health (CVH) score vs. Lower CVH score was evaluated on Progression of brachial-ankle pulse wave velocity (baPWV). A higher cardiovascular health score was associated with lower baseline and follow-up brachial-ankle pulse wave velocity, which increased overall from a median of 1340 cm/s to 1400 cm/s over 4 years.