Female sex increased the risk of developing dementia compared to male sex in atrial fibrillation patients aged >56 years (e.g., SHR 1.14, 95% CI 1.09-1.20 for ages 66-75).
Cohort (n=200,130)
Yes
Does female sex increase the risk of dementia in patients with atrial fibrillation compared to male sex?
Female sex is associated with an increased risk of developing dementia compared to male sex in patients with atrial fibrillation aged over 56 years.
Effect estimate: SHR 1.14 (95% CI 1.09-1.20)
Atrial fibrillation (AF) is one of the risk factors for dementia. Female sex is an inconsistent risk factor for dementia after adjusting for age in the general population, and there lacks research on its impact in developing dementia in patients with AF. This paper aims to investigate whether female sex is a risk factor for dementia in AF patients. Data of patients with newly diagnosed AF between 2001-2013 were retrieved from Taiwan's National Health Insurance Research Database. Exclusion criteria were: patients with incomplete demographic data, age 85 years (SHR 1.10, 95% CI 1.04-1.16) for females. This study establishes that female sex increases the risk of developing dementia compared to male sex in AF patients aged >56 years. However, the impact of female sex on dementia in AF patients differs between dementia types.
Chen et al. (Fri,) conducted a cohort in Atrial Fibrillation (n=200,130). Female sex vs. Male sex was evaluated on New diagnosis of dementia at follow-up (SHR 1.14, 95% CI 1.09-1.20). Female sex increased the risk of developing dementia compared to male sex in atrial fibrillation patients aged >56 years (e.g., SHR 1.14, 95% CI 1.09-1.20 for ages 66-75).
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