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Introduction use of e-cigarettes has been the subject of a public health debate their possibility of undermining efforts for tobacco control. The aim of this was to synthesize the risk of smoking relapse with the use of e-cigarettes former smokers. , EMBASE, PsycInfo and LILACS were searched without to language or date of publication. Longitudinal observational studies the association between e-cigarette use and smoking relapse were by two independent reviewers, and disagreements solved by discussion a third researcher. Data extraction and risk of bias assessment were also out by two independent reviewers. The meta-analysis was performed the random effect Mantel-Haenszel model. 632 retrieved records, six studies were eligible and described, while were included in the quantitative synthesis. The studies were conducted the USA, UK and France, with final sample size varying from 374 to 4094 smokers. Risk of relapse was 2. 03 (95% CI: 1. 39–2. 96) among former users than non-users of e-cigarettes, and 1. 38 (95% CI: 1. 11–1. 65) when the adjusted association measures. Long-term former smokers were the contributors for the higher relapse risk, while the impact of frequency of to e-cigarettes (past, non-daily, daily) was uncertain. the growing popularity of e-cigarettes among former, our results point to the great potential for an increase in the frequency relapse to conventional smoking and vaping for those who move to regular of e-cigarettes.
Barufaldi et al. (Mon,) studied this question.