The early repolarization pattern was highly prevalent in physically active individuals (33.9%) compared to the general population (11.6%), with higher rates also seen in men and Black individuals.
Meta-Analysis (n=190,222)
Yes
What is the worldwide prevalence of early repolarization pattern in the general population and physically active individuals?
Early repolarization pattern is highly prevalent worldwide, particularly among men, Black individuals, and physically active individuals, with a pooled prevalence of 11.6% in the general population and 33.9% in physically active individuals.
Absolute Event Rate: 33.9% vs 11.6%
BACKGROUND: The early repolarization pattern (ERP) has recently been associated with cardiac events such as ventricular arrhythmias and sudden cardiac death. However, estimates of the prevalence of ERP vary widely, especially between the general population and physically active individuals. We performed this systematic review and meta-analysis to quantitatively evaluate the worldwide prevalence of ERP in the general population and physically active individuals. METHODS: We thoroughly searched the PubMed, EMBASE, Web of science, the Cochrane Library, and Scopus databases for relevant studies published until December 20, 2020. Studies in which prevalence was presented or could be estimated from eligible data were included. The pooled prevalence was analyzed using a random-effect model. RESULTS: Finally, we included 29 studies (182,135 subjects) in the general population and 14 studies (8087 subjects) in the physically active individuals. The worldwide pooled prevalence of ERP in the general population was 11.6% (95% confidence interval CI: 10.0%-13.3%). The incidence of ERP was 17.0% and 6.2% in men and women, respectively. The prevalence was 20.9% in blacks, 13.4% in Asians, and 10.1% in Caucasians. Additionally, the prevalence of ERP in physically active individuals was 33.9% (95% CI: 25.3%-42.6%). CONCLUSION: A significant difference in the worldwide prevalence of ERP is revealed in this study. The ERP is highly prevalent in men, blacks, and physically active individuals.
Ji et al. (Fri,) conducted a meta-analysis in Early repolarization pattern (n=190,222). Physically active status vs. General population was evaluated on Prevalence of early repolarization pattern. The early repolarization pattern was highly prevalent in physically active individuals (33.9%) compared to the general population (11.6%), with higher rates also seen in men and Black individuals.