Analysis of global databases from 2000 to 2015 revealed a 7% increase in age-standardized cancer mortality (P<.00001) alongside a significant decrease in cardiovascular disease mortality (P<.00001).
Observational
Yes
Global mortality trends from 2000 to 2015 show a significant decrease in cardiovascular disease mortality alongside a 7% increase in cancer mortality, suggesting cancer may soon surpass cardiovascular disease as the leading cause of death.
Effect estimate: 7% increase
p-value: p=<.00001
ObjectiveTo highlight the current global trends in mortality for cardiovascular disease and cancer.MethodsThe World Health Organization and the World Bank DataBank databases were used to analyze mortality rates for cancer and cardiovascular disease by calculating age-standardized mortality rates (ASRs) from 2000 to 2015 for high-income, upper-middle-income, and lower-middle-income countries. Data for cancer mortality and population for 43 countries representing 5 of the 7 continents (except Australia and Antarctica) were analyzed.ResultsFrom 2000 to 2015, there was an increase in the ASR for cancer for both men and women irrespective of a country’s income status, representing an overall 7% increase in cancer ASR (Pearson r, +0.99; P<.00001). We report a higher ASR for cancer in high-income countries than in upper-middle-income and lower-middle-income countries specifically; high-income countries saw a 3% increase in cancer ASR vs +31% for upper-middle-income and +19% for lower-middle-income countries (P<.01). There has been a decrease in the ASR for cardiovascular disease for the 15 years analyzed (P<.00001). In addition, high-income countries had a higher ASR for cardiovascular disease than upper-middle-income countries during the 15-year period (P<.05).ConclusionWe suspect that because of early detection and targeted interventions, cardiovascular disease mortality rates have decreased during the past decade. On the basis of our results, cancer mortality rates continue to rise, with the projection of surpassing cardiovascular disease mortality rates in the near future.
ReFaey et al. (Tue,) conducted a observational in Cardiovascular disease and cancer. Analysis of global databases from 2000 to 2015 revealed a 7% increase in age-standardized cancer mortality (P<.00001) alongside a significant decrease in cardiovascular disease mortality (P<.00001).
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