CAVI0 may enhance the pressure-independent assessment of arterial stiffness compared to CAVI, especially in the presence of large inter-individual differences in blood pressure.
Does CAVI0 provide a more pressure-independent assessment of arterial stiffness compared to CAVI?
CAVI0 may offer a more pressure-independent metric of arterial stiffness than the traditional CAVI, potentially improving cardiovascular risk assessment.
Pulse wave velocity, a common metric of arterial stiffness, is an established predictor for cardiovascular events and mortality. However, its intrinsic pressure-dependency complicates the discrimination of acute and chronic impacts of increased blood pressure on arterial stiffness. Cardio-ankle vascular index (CAVI) represented a significant step towards the development of a pressure-independent arterial stiffness metric. However, some potential limitations of CAVI might render this arterial stiffness metric less pressure-independent than originally thought. For this reason, we later introduced CAVI0. Nevertheless, advantages of one approach over the other are left debated. This review aims to shed light on the pressure (in)dependency of both CAVI and CAVI0. By critically reviewing results from studies reporting both CAVI and CAVI0 and using simple analytical methods, we show that CAVI0 may enhance the pressure-independent assessment of arterial stiffness, especially in the presence of large inter-individual differences in blood pressure.
Giudici et al. (Thu,) conducted a review in Arterial stiffness. CAVI0 vs. CAVI was evaluated on Pressure-independent assessment of arterial stiffness. CAVI0 may enhance the pressure-independent assessment of arterial stiffness compared to CAVI, especially in the presence of large inter-individual differences in blood pressure.