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Obesity prevalence is increasing worldwide, with significant healthcare implications. We searched PubMed/MEDLINE, Embase and the Cochrane Library for articles registered until June 2020 to explore the relationship between obesity and urinary (UI) and anal incontinence (AI). Obesity is associated with low-grade, systemic inflammation and proinflammatory cytokine release, producing reactive oxygen species and oxidative stress. This alters collagen metabolism and, in combination with increased intra-abdominal pressure, contributes to the development of UI. Whereas in AI, stool consistency may be a factor. Weight loss can reduce UI and should be a management focus; however, the effect of weight loss on AI is less clear.
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Stergios K. Doumouchtsis
Jemina Loganathan
Vasilios Pergialiotis
BJOG An International Journal of Obstetrics & Gynaecology
National and Kapodistrian University of Athens
St George's, University of London
Epsom and St Helier University Hospitals NHS Trust
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Doumouchtsis et al. (Tue,) studied this question.
www.synapsesocial.com/papers/6a05045521b736d53b0af073 — DOI: https://doi.org/10.1111/1471-0528.16848
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