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. This unique, multipronged approach leads to the characterization of a phenylpyrrolocytosine (PhpC)-based G-clamp analog as a prototype of G4-disrupting small molecule whose properties are validated through many different and complementary in vitro evaluations.
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Jérémie Mitteaux
Pauline Lejault
Filip Wojciechowski
Journal of the American Chemical Society
Centre National de la Recherche Scientifique
Inserm
Sorbonne Université
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Mitteaux et al. (Wed,) studied this question.
www.synapsesocial.com/papers/6a0358c1200d7a04bd7562ab — DOI: https://doi.org/10.1021/jacs.1c04426