Compared with the lowest decile, the highest decile of a body shape index (ABSI) was associated with increased odds of subclinical carotid atherosclerosis in males (OR 1.87) and females (OR 2.83).
Cross-Sectional (n=5,245)
No
Does a body shape index (ABSI) associate with subclinical carotid atherosclerosis in a population free of cardiovascular and cerebrovascular diseases?
A body shape index (ABSI) is independently associated with subclinical carotid atherosclerosis in a population free of cardiovascular disease, outperforming traditional obesity indices like BMI.
Odds Ratio: 1.87 (95% CI 1.17–3)
Absolute Event Rate: 43.43% vs 19.6%
p-value: p=0.009
AIM: We used a dataset from a cross-sectional survey conducted in China to determine which of the anthropometric indices of obesity are important in terms of carotid atherosclerosis free of cardiovascular and cerebrovascular diseases. METHODS: A total of 5,245 participants who were volunteering for carotid ultrasound unit in this cross-sectional survey were included in the present analysis. All subjects were free of angina, myocardial infarction, heart failure and stroke, and cancer. A low-risk subgroup was defined as people free of hypertension, diabetes, and hyperlipidemia. All analyses based on logistic regression were gender-specific. RESULTS: The present study consisted of 2,501 males and 2,744 females, with 776 (31.03%) diagnosed as carotid artery plaque in males and 550 (20.04%) in females. Univariable analyses in unadjusted logistic model showed significant associations between disease presence and all central obesity indices. After adjusting for more variables, only a body shape index (ABSI) was associated with the presence of disease in both males and females. Moreover, stepwise regression approaches revealed that ABSI was always an independent determinant of the presence of subclinical carotid plaque. Multiple regression shows a linear and significant increase in the prevalence of atherosclerosis in males and females as ABSI decile levels increased. Similar results were obtained when the association between ABSI and carotid plaque was studied in this low-risk subgroup. CONCLUSIONS: ABSI, as a novel anthropometric indicator compared with traditional indices, was found to have a closer relationship with subclinical carotid atherosclerosis, even in populations free of hypertension, diabetes, and hyperlipidemia.
Ma et al. (Fri,) conducted a cross-sectional in Subclinical carotid atherosclerosis (n=5,245). A body shape index (ABSI) vs. Lowest decile of ABSI was evaluated on Presence of subclinical carotid atherosclerosis (males, highest vs lowest ABSI decile) (OR 1.87, 95% CI 1.17-3.00, p=0.009). Compared with the lowest decile, the highest decile of a body shape index (ABSI) was associated with increased odds of subclinical carotid atherosclerosis in males (OR 1.87) and females (OR 2.83).