Bicuspid aortic valve is associated with a high risk of progressive aortic dilatation, necessitating regular imaging surveillance and timely surgical intervention to prevent dissection or rupture.
This comprehensive review synthesizes current knowledge on the clinical definitions, epidemiology, natural history, and pathophysiology of bicuspid aortic valve aortopathy.
Bicuspid aortic valve (BAV) is the most common congenital cardiac abnormality. BAV aortic dilatation is associated with an increased risk of adverse aortic events and represents a potentially lethal disease and hence a considerable medical burden. BAV with aortic dilatation warrants frequent monitoring, and elective surgical intervention is the only effective method to prevent dissection or rupture. The predictive value of the aortic diameter is known to be limited. The aortic diameter is presently still the main reference standard for surgical intervention owing to the lack of a comprehensive understanding of BAV aortopathy progression. This article provides a brief comprehensive review of the current knowledge on BAV aortopathy regarding clinical definitions, epidemiology, natural course, and pathophysiology, as well as hemodynamic and clinically significant aspects on the basis of the limited data available.
Wang et al. (Tue,) conducted a review in Bicuspid Aortic Valve (BAV) with Aortic Dilatation. Bicuspid aortic valve is associated with a high risk of progressive aortic dilatation, necessitating regular imaging surveillance and timely surgical intervention to prevent dissection or rupture.
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