Cardiac rehabilitation improved functional outcomes in both groups, with obese patients reaching similar post-rehabilitation physical activity levels as non-obese patients (6.79 vs 7.33 METS, p=0.200) despite no associated weight loss.
Cohort (n=178)
No
Does comprehensive phase II cardiac rehabilitation improve functional outcomes differently in obese compared to non-obese patients with cardiovascular disease?
Cardiac rehabilitation improves functional outcomes such as chronotropic competence and metabolic equivalents in both obese and non-obese patients, irrespective of weight loss, though blood pressure response improvement was limited to non-obese patients.
Absolute Event Rate: 6.79% vs 7.33%
p-value: p=0.200
Background Cardiac rehabilitation (CR) improves outcomes in patients with heart disease. We investigated the differences in outcomes of comprehensive phase II CR in obese and non-obese patients. Methods We performed a retrospective analysis of functional outcomes including metabolic equivalents (METS), heart rate (chronotropic competence - CC), and blood pressure response (BPR) in 178 patients undergoing CR based on underlying body mass index (BMI). Demographic and clinical variables were assessed for age, gender, race, smoking, hypertension, hyperlipidemia, diabetes mellitus, coronary artery disease, stroke, heart failure, medication use, and several sessions attended. Results Initial CC and METS were impaired in majority of patients attending CR, whereas BPR to exercise was mostly preserved. Significant improvement occurred in CC (non-obese: 0.71 ± 0.11 vs 0.76 ± 0.11, p 0.05). Conclusion CR concurrently improves functional outcomes in both obese and non-obese patients despite no associated weight loss. The difference in BPR, however, is seen in only non-obese individuals. Future studies are needed to validate the role of weight-optimized CR protocols as a potential target for improving cardiac outcomes.
Atti et al. (Thu,) conducted a cohort in Cardiovascular disease (n=178). Cardiac Rehabilitation vs. Non-obese patients (BMI < 30 kg/m2) was evaluated on Post-rehabilitation Metabolic Equivalents (METS) (p=0.200). Cardiac rehabilitation improved functional outcomes in both groups, with obese patients reaching similar post-rehabilitation physical activity levels as non-obese patients (6.79 vs 7.33 METS, p=0.200) despite no associated weight loss.