October 7, 2021Open Access

Glucose and high-sensitivity troponin T predict a low risk of major adverse cardiac events in emergency department chest pain patients

PCPontus Olsson de CapretzLund University AKArdavan KhoshnoodGeneral Cardiology AMArash MokhtariGeneral Cardiology

Structured PICO

Does the combination of hs-cTnT and blood glucose at presentation improve the identification of ED chest pain patients at low risk for 30-day MACE?

Population

Emergency department patients presenting with chest pain

Intervention

Risk stratification using a combination of high-sensitivity troponin T (hs-cTnT) and blood glucose at presentation

Comparator

hs-cTnT alone (implied for rule-in)

Outcome

30-day major adverse cardiac events (MACE)composite

Combining hs-cTnT and blood glucose at presentation can safely rule out 30-day MACE in nearly a quarter of ED patients with chest pain, potentially reducing unnecessary further testing.

Abstract

A combination of hs-cTnT and blood glucose at presentation can be used to identify almost ¼ of ED chest pain patients with a very low risk of 30-day MACE where further testing is not needed. Adding glucose did not improve the rule-in of 30-day MACE.

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