Echocardiographic estimation of pulmonary artery systolic pressure in lung transplant candidates showed moderate correlation with right heart catheterization (r=0.609, p<0.01) and poor accuracy.
Observational (n=393)
Does echocardiography accurately estimate pulmonary artery systolic pressure compared to right heart catheterization in lung transplant candidates?
Echocardiographic estimation of PASP has only moderate correlation and poor accuracy compared to RHC in lung transplant candidates, suggesting RHC remains necessary for accurate hemodynamic assessment.
Effect estimate: r=0.609
Absolute Event Rate: 49.5% vs 42.47%
p-value: p=<0.01
Abstract Background Right heart catheterization (RHC) and echocardiography are both routinely used for pulmonary hypertension (PH) assessment in LT candidates, although this is not mandatory according to guidelines. We aim to describe the correlation between the pulmonary artery systolic pressure (PASP) measured by echocardiography to that measured by RHC in this population. Methods From a retrospective registry of 461 LT candidates, undergoing RHC between 2015–2019, 393 consecutive patients were assessed for the presence of pulmonary hypertension according to two methods – echocardiography and RHC. The primary outcome was the correlation between the estimated PASP measured by echocardiography to that measured by RHC. Secondary outcome was the accuracy of the echocardiographic assessment of PH. Results Patients were predominantly males (63.6%) with a mean age of 61.46±8.33y. The two most common etiologies for lung failure were interstitial lung disease or pulmonary fibrosis (52.2%) and chronic obstructive pulmonary disease (30.5%). Estimated PASP as measured by echocardiography was available in 89.31% of the patients, with a mean value of 49.5±20.02 mmHg. Mean PASP measured by RHC was 42.47±17.96 mmHg. The correlation between the two measurements was moderate (Pearson's correlation: r=0.609, p0.01). The accuracy of the echocardiographic estimation of PASP was poor with 10 mmHg differences between the two values in 79.9% of the patients. Conclusions In the pre-surgical evaluation of LT candidates, echocardiographic estimation of PASP has moderate correlation with the PASP measured by RHC and relatively poor accuracy. Funding Acknowledgement Type of funding sources: None.
Skalsky et al. (Fri,) conducted a observational in Lung transplant candidates (n=393). Echocardiography vs. Right heart catheterization was evaluated on Correlation between the estimated PASP measured by echocardiography to that measured by RHC (r=0.609, p=<0.01). Echocardiographic estimation of pulmonary artery systolic pressure in lung transplant candidates showed moderate correlation with right heart catheterization (r=0.609, p<0.01) and poor accuracy.