Among individuals without cardiovascular disease, NT-proBNP and hs-cTnT were poorly correlated at baseline (rho 0.083) and demonstrated differential associations with demographic and cardiac factors.
Cohort (n=1,877)
No
Without known cardiovascular disease (n=1,877)
NT-proBNP and hs-cTnT measurement
Correlation between baseline NT-proBNP and hs-cTnT — Spearman rho 0.083, p=0.015
Effect estimate: Spearman rho 0.083
p-value: p=0.015
Among individuals without CVD in the general population, NT-proBNP and hs-cTnT are nonredundant biomarkers that are differentially associated with demographic and cardiac factors. These findings indicate that hs-cTnT and NT-proBNP may reflect different pathophysiological pathways.
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Christopher W Puleo
Ochsner Medical Center
Colby Ayers
Preventive Cardiology
Sonia Garg
Heart Failure / Cardiomyopathy
Biomarkers in Medicine
The University of Texas Southwestern Medical Center
Ochsner Medical Center
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Puleo et al. (Tue,) conducted a cohort in Without known cardiovascular disease (n=1,877). NT-proBNP and hs-cTnT measurement was evaluated on Correlation between baseline NT-proBNP and hs-cTnT (Spearman rho 0.083, p=0.015). Among individuals without cardiovascular disease, NT-proBNP and hs-cTnT were poorly correlated at baseline (rho 0.083) and demonstrated differential associations with demographic and cardiac factors.
synapsesocial.com/papers/6a12c6b983732aa7db9e4a36 — DOI: https://doi.org/10.2217/bmm-2021-0055