October 28, 2021Open Access

Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set

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Abstract

The findings of this cohort study suggest that this new classification, Li-Fraumeni spectrum, is a step toward understanding the factors that lead to phenotypic differences and may serve as a model for other cancer predisposition syndromes.

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Authors

Christian P. Kratz

Claire Freyçon

Kara N. Maxwell

Journals

JAMA Oncology

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Institutions

Harvard University

National Institutes of Health

University of Pennsylvania

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Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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