Does concomitant tricuspid repair reduce primary-end-point events in patients with degenerative mitral regurgitation undergoing mitral-valve surgery?
Patients with degenerative mitral regurgitation undergoing mitral-valve surgery
Concomitant tricuspid repair (TA)
Mitral-valve surgery alone
Primary-end-point event at 2 yearscomposite
Concomitant tricuspid repair during mitral-valve surgery reduces progression to severe tricuspid regurgitation at 2 years but increases the risk of permanent pacemaker implantation.
Among patients undergoing mitral-valve surgery, those who also received TA had a lower incidence of a primary-end-point event than those who underwent mitral-valve surgery alone at 2 years, a reduction that was driven by less frequent progression to severe tricuspid regurgitation. Tricuspid repair resulted in more frequent permanent pacemaker implantation. Whether reduced progression of tricuspid regurgitation results in long-term clinical benefit can be determined only with longer follow-up. (Funded by the National Heart, Lung, and Blood Institute and the German Center for Cardiovascular Research; ClinicalTrials.gov number, NCT02675244.).
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James S. Gammie
Michael Chu
Volkmar Falk
New England Journal of Medicine
Johns Hopkins University
National Institutes of Health
Yale University
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Gammie et al. (Sat,) studied this question.
www.synapsesocial.com/papers/69de9d075e582bd3c5e93dc8 — DOI: https://doi.org/10.1056/nejmoa2115961