Shorter admission pulmonary vein S and D wave peak velocities, IVRT, and DT were significant predictors of medical cardioversion failure with amiodarone in acute atrial fibrillation (p<0.001).
Observational (n=40)
Do baseline diastolic echocardiographic parameters predict the success of medical cardioversion with intravenous amiodarone in patients with acute atrial fibrillation?
Baseline diastolic parameters, including pulmonary vein velocities, IVRT, DT, and Pro-BNP levels, may predict the failure of medical cardioversion with amiodarone in patients with acute atrial fibrillation.
p-value: p=<0.001
BACKGROUND: Diastolic function assessment has been reported to provide valuable data in patients with atrial fibrillation (AF). The purpose of this study was to evaluate the effects of diastolic parameters on predicting the effectiveness of medical cardioversion in restoring sinus rhythm among patients with acute AF. METHODS: 40 non-valvular, new onset AF patients were included. All participants received an intravenous infusion of amiodarone. In patients whom sinus rhythm could not be restored with amiodarone, an electrical cardioversion was performed. Two groups, patients who achieved sinus rhythm with amiodarone (Group-1) and who failed to achieve sinus rhythm with amiodarone (Group-2) were compared with respect to initial echocardiographic measurements. RESULTS: , p = 0.03); a shorter pulmonary vein S (49.6 ± 3.8 cm/sec vs 41.1 ± 3.0 cm/sec, p < 0.001); and a shorter pulmonary vein D peak velocity (55.9 ± 2.4 cm/sec vs 52.3 ± 1.8 cm/sec, p < 0.001). Moreover, both IVRT and DT were significantly shorter in Group-2, comparing with Group-1 (45.1 ± 2.1 msec vs 51.1 ± 2.5 msec, p < 0.001 and 51.3 ± 2.4 msec vs 56.5± 3.2 msec, p < 0.001, respectively). CONCLUSION: The present study revealed that admission pulmonary vein S and D wave peak velocities, IVRT, DT, and Pro-BNP levels could be predictors of failure of medical cardioversion among AF patients.
Yaşan et al. (Thu,) conducted a observational in Acute atrial fibrillation (n=40). Intravenous amiodarone was evaluated on Effectiveness of medical cardioversion in restoring sinus rhythm (p=<0.001). Shorter admission pulmonary vein S and D wave peak velocities, IVRT, and DT were significant predictors of medical cardioversion failure with amiodarone in acute atrial fibrillation (p<0.001).