Ascertaining Death Events in a Pragmatic Clinical Trial: Insights From the TRANSFORM-HF Trial

Key Points

• The research aims to determine how death events are recorded in a pragmatic clinical trial focused on heart failure.
• Conducted as part of the TRANSFORM-HF trial
• Analyzed death events within the framework of pragmatic clinical methodology
• Utilized a randomized trial design encompassing diverse heart failure outcomes
• Identified specific criteria for ascertaining death events
• Highlighted variations in reporting methods among centers
• Provided recommendations for standardized death event documentation