Does prompt invasive coronary angiography and revascularization reduce mortality in patients with acute coronary syndromes?
Patients with acute coronary syndromes, specifically STEMI and high-risk NSTE-ACS without contraindications
Prompt invasive coronary angiography followed by percutaneous coronary intervention (PCI) or surgical revascularization (within 2 hours of presentation for STEMI)
Mortalityhard clinical
Prompt invasive evaluation and revascularization are critical for reducing mortality in patients presenting with STEMI or high-risk NSTE-ACS.
Each year, an estimated more than 7 million people are diagnosed with ACS worldwide. For patients with STEMI, coronary catheterization and PCI within 2 hours of presentation reduces mortality, with fibrinolytic therapy reserved for patients without access to immediate PCI. For high-risk patients with NSTE-ACS without contraindications, prompt invasive coronary angiography followed by percutaneous or surgical revascularization is associated with lower rates of death.
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Deepak L. Bhatt
Renato D. Lópes
Robert A. Harrington
JAMA
Harvard University
Stanford University
Brigham and Women's Hospital
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Bhatt et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d6b9aa75cae9790bed8956 — DOI: https://doi.org/10.1001/jama.2022.0358