Does MR angiography quantitatively evaluate age-related tortuosity and hemodynamic alterations in carotid and vertebral arteries across the adult lifespan?
Large cohort of populations covering adult lifespan (general population)
MR Angiography (vascular auto-segmentation, centerline tracking, and phase mapping)
Age-related morphological and hemodynamic alterations (tortuosity and blood flow)surrogate
MR angiography provides quantitative reference ranges for age-related morphological and hemodynamic alterations in neck arteries across the adult lifespan.
Vascular auto-segmentation, centerline tracking, and phase mapping provide promising quantitative assessments of tortuosity and its effects on blood flow. The neck arteries demonstrate quantifiable and significant age-related morphological and hemodynamic alterations. Moreover, females showed more distinct vascular changes with age. Our work is built upon a comprehensive quantitative investigation of a large cohort of populations covering adult lifespan using MRI, the results can serve as reference ranges of each decade in the general population.
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Zhe Sun
Second Affiliated Hospital of Zhejiang University
Dengrong Jiang
Johns Hopkins University
Peiying Liu
University of Maryland, Baltimore
SHILAP Revista de lepidopterología
Frontiers in Neurology
Johns Hopkins University
New York University
Johns Hopkins Medicine
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Sun et al. (Fri,) studied this question.
synapsesocial.com/papers/69df22e8b8d7e945666149cb — DOI: https://doi.org/10.3389/fneur.2022.858805
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